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Best chemical phenols, ranked

Cutting through the noise on what to actually buy.

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Best chemical phenols, ranked

AI-generated summary · updated July 29, 2026 · verify details before purchase.

  1. Best overall

    Thermo Scientific Pierce Phenol, Saturated, 100 mL

    4.6/5 $50-$70

    High-purity saturated phenol for DNA/RNA extraction, widely trusted in molecular biology labs.

    • High purity
    • Consistent quality
    • Good for nucleic acid extraction
    • Expensive per mL
    • Saturated solution may require pH adjustment
    View on Amazon manufacturer site
  2. Best for bulk use

    MP Biomedicals 901025 Phenol, Crystalline, 500 g

    $80-$120

    Crystalline phenol suitable for large-scale synthesis and industrial applications.

    • Large quantity
    • Cost-effective per gram
    • High purity grade
    • Requires melting before use
    • Not pre-equilibrated
    View on Amazon manufacturer site
  3. Best for analytical chemistry

    Sigma-Aldrich P1037 Phenol, ≥99.5%, 1 L

    4.5/5 $90-$140

    Analytical grade phenol with high purity, ideal for chromatography and spectroscopy.

    • Very high purity
    • Consistent lot-to-lot
    • Low water content
    • Expensive
    • Large container may be excessive for small labs
    View on Amazon manufacturer site
  4. Best budget pick

    Fisher Chemical A931-1 Phenol, Liquified, 500 mL

    4.4/5 $60-$90

    ACS-grade liquified phenol at a competitive price, suitable for general lab use.

    • Affordable
    • ACS grade
    • Ready to use
    • Not as pure as premium brands
    • Shorter shelf life once opened
    View on Amazon manufacturer site
  5. Best value bulk

    Alfa Aesar A11281 Phenol, 99+%, 2.5 kg

    $150-$200

    High-purity phenol in bulk packaging, ideal for industrial labs with high consumption.

    • Low cost per gram
    • Large quantity
    • Good purity
    • Very large container
    • Limited availability
    View on Amazon manufacturer site
  6. Best for synthesis

    ACROS Organics 327321000 Phenol, Crystalline, 1 kg

    4.3/5 $100-$140

    Crystalline phenol perfect for organic synthesis and as a reagent.

    • Crystalline form
    • Good purity
    • Suitable for synthesis
    • Must be melted before use
    • Hygroscopic
    View on Amazon manufacturer site
  7. Best economy option

    Chem-Impex 00112 Phenol, Liquified, 1 L

    $40-$60

    Budget-friendly liquified phenol for routine lab procedures where high purity is not critical.

    • Very low price
    • Suitable for basic extractions
    • Available in large volume
    • Variable quality
    • May contain impurities
    View on Amazon

What to consider before buying

When buying phenol, consider purity requirements: ACS grade is sufficient for most extractions, while higher purity (99.5%+) is needed for chromatography. Liquid phenol is convenient, but crystalline may offer better stability if stored properly. Bulk purchases reduce per-unit cost but require proper handling and storage (inert atmosphere, away from light). Always check safety data and use appropriate PPE.

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