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Chemical resistant gloves: top picks

AI-generated summary · updated September 11, 2026 · verify details before purchase.

  1. Ansell AlphaTec 58-535W ChemTek
    Best overall Ansell

    Ansell AlphaTec 58-535W ChemTek

    4.3/5 $83.98

    High chemical resistance with excellent dexterity; ideal for handling hazardous liquids and solvents.

    • Excellent chemical barrier
    • Good flexibility
    • Durable construction
    • Slightly expensive
    • Limited color options
  2. Showa 374-10 Chemik
    Best value SHOWA

    Showa 374-10 Chemik

    4.2/5 $69.99 Only 1 left

    Affordable yet reliable chemical protection for light to moderate tasks; good for janitorial and lab use.

    • Cost-effective
    • Comfortable fit
    • Good grip
    • Less durable than heavy-duty options
    • Not for strong acids
  3. 3M G500 Nitrile Chemical Gloves
    Best budget pick ThxToms

    3M G500 Nitrile Chemical Gloves

    4.4/5 $7.99

    Thin nitrile gloves with good chemical splash resistance; popular for automotive and cleaning tasks.

    • Very affordable
    • Good dexterity
    • Powder-free
    • Limited chemical resistance for strong solvents
    • Can tear easily
  4. Best for solvents

    Honeywell Sol-Vex 37-145

    4.3/5 $30-$50

    Durable nitrile glove with excellent resistance to solvents and petroleum products; trusted by professionals.

    • Excellent solvent resistance
    • Long service life
    • Good grip
    • Less flexible in cold
    • Slightly stiff initially
  5. Best extreme protection

    MAPa 2-222 Ultra Chem

    4.5/5 $80-$120

    Multi-layer glove offering extreme chemical resistance for hazardous materials and industrial use.

    • Highest chemical protection
    • Very durable
    • Comfortable for extended wear
    • Very expensive
    • Less dexterous
  6. Kimtech G3 Sterile Nitrile Gloves
    Best for cleanrooms Kimberly-Clark

    Kimtech G3 Sterile Nitrile Gloves

    4.1/5 $70.30

    Premium sterile gloves with good chemical splash protection; suitable for pharmaceutical and cleanroom environments.

    • Sterile and cleanroom safe
    • High quality
    • Good chemical resistance
    • Pricey
    • Not for heavy-duty chemical handling
  7. Best heat + chemical

    Bayport Zetex Plus Silver Gloves

    4.0/5 $100-$150

    Combines heat and chemical resistance with a silver lining; ideal for auto repair and foundry work.

    • Heat and chemical resistant
    • Durable
    • Reflective lining
    • Expensive and bulky
    • Limited dexterity

What to consider before buying

When choosing chemical resistant gloves, consider the specific chemicals being handled (check chemical compatibility charts), required dexterity, glove material (nitrile, neoprene, butyl, etc.), and thickness. Ensure gloves meet industry standards (e.g., EN 374). For budget-friendly options, 3M G500 offers good value for light tasks, while Ansell AlphaTec provides robust protection for more demanding jobs. Always inspect gloves for damage before use and replace when worn.

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