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Top rated lab surfactants and detergents

AI-generated summary · updated July 29, 2026 · verify details before purchase.

  1. Tergazyme Enzyme-Active Lab Detergent, 4 lb
    Best overall Alconox

    Tergazyme Enzyme-Active Lab Detergent, 4 lb

    4.7/5 $2,593.90

    Highly effective enzymatic detergent for manual and automated cleaning of lab glassware and instruments.

    • Excellent cleaning power
    • Dissolves quickly
    • Works with cold water
    • Slightly expensive
    • Powder can clump if not sealed
  2. Alconox Lab Detergent, 12 lb
    Best value Alconox

    Alconox Lab Detergent, 12 lb

    4.8/5 $65.99

    Versatile and economical detergent suitable for a wide range of lab cleaning tasks.

    • Cost-effective per use
    • Effective on grease
    • Low residue
    • Not enzymatic
    • Large container may be bulky
  3. Best for general use

    Sigma-Aldrich 5% Liqui-Nox Laboratory Detergent, 1 gal

    4.6/5 $40-$60

    Popular liquid detergent for general lab cleaning, safe on metals and plastics.

    • Ready-to-use liquid
    • Non-toxic
    • Versatile
    • Requires rinsing
    • May not remove stubborn residues
  4. Decon Contrex 2X Heavy-Duty Alkaline Detergent, 1 gal
    Best for tough residues Decon Labs

    Decon Contrex 2X Heavy-Duty Alkaline Detergent, 1 gal

    4.5/5 $58.70

    Concentrated alkaline detergent ideal for removing heavy organic soils and carbonized residues.

    • Powerful degreasing
    • Concentrated formula
    • Effective on baked-on soils
    • Caustic, requires PPE
    • Expensive
  5. Best for glassware

    Thermo Scientific RBS 35 Detergent, 1 L

    4.4/5 $30-$50

    Non-foaming, phosphate-free detergent specially formulated for lab glassware cleaning in washers.

    • Phosphate-free
    • Leaves glass spot-free
    • Automatic washer compatible
    • Not for manual cleaning
    • Pricey per liter
  6. Micro-90 Lab Cleaning Solution, 1 gal
    Best for precision instruments Cole-Parmer

    Micro-90 Lab Cleaning Solution, 1 gal

    4.3/5 $41.50

    Concentrated, biodegradable cleaner safe for delicate instruments and optical surfaces.

    • Non-abrasive
    • Biodegradable
    • Safe on optics
    • Expensive concentrate
    • May need multiple rinses
  7. Cole-Parmer Lab Detergent Powder, 2 lb
    Best budget pick Oakton

    Cole-Parmer Lab Detergent Powder, 2 lb

    4.5/5 $46.50

    Economical powder detergent for basic lab cleaning needs, effective and inexpensive.

    • Very affordable
    • Good for routine cleaning
    • Easy to store
    • Less effective on tough soils
    • Not for precision instruments

Buying advice

When choosing a lab detergent, consider the type of residue you need to remove (e.g., organic, proteinaceous) and whether you need enzymatic action. For routine glassware, a neutral detergent like Alconox offers good value. For heavily soiled or sensitive instruments, consider enzyme-active or alkaline formulations. Always check compatibility with your materials and follow safety guidelines for concentrated products. Price per use often matters more than upfront cost.

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